Formulated by Science. Verified by Labs. Trusted by Longevity Seekers.

Same Pure NMN Used in Human Clinical Trials
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules

Free Shipping

US orders over $50 and international over $100 

Money-Back Guarantee

Peace of mind with our 60-day money-back guarantee.

Free Shipping

US orders over $50 and international over $100 

Money-Back Guarantee

Peace of mind with our 60-day money-back guarantee.

The HealthspanX Standard™
Where Clinical Purity Meets Real-World Results

At HealthspanX, we don’t cut corners—we cut through noise. Our Ultra Pure NMN™ uses the same pharmaceutical-grade ingredient tested in human trials, with purity over 99% and trusted by health professionals who demand real results. No gimmicks, no fillers—just clean, bioavailable NMN to elevate NAD+, fuel mitochondria, and restore vitality at the cellular level. Don’t settle for what’s trending. Choose what’s tested.
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules
Ultra Pure NMN™ 500mg, 62 Capsules

Ultra Pure NMN™ 500mg, 62 Capsules

Based on Verified Customers

NAD+ levels decline with age, reducing energy, mental clarity, and skin health. Ultra Pure NMN™ is clinically formulated to restore NAD+, powering energy production, DNA repair, and cellular renewal.

Experience renewed energy, lasting vitality, sharper focus, and cellular skin renewal — all from the inside out. Whether you're managing stress or simply aging proactively, Ultra Pure NMN™ is your trusted daily boost.
$76.00
$0.00

Delivery Size - Daily Dosage

The HealthspanX Standard™
Where Clinical Purity Meets Real-World Results

At HealthspanX, we don’t cut corners—we cut through noise. Our Ultra Pure NMN™ uses the same pharmaceutical-grade ingredient tested in human trials, with purity over 99% and trusted by health professionals who demand real results. No gimmicks, no fillers—just clean, bioavailable NMN to elevate NAD+, fuel mitochondria, and restore vitality at the cellular level. Don’t settle for what’s trending. Choose what’s tested.

  • Science

  • Formula

  • Usage

  • Lab Testing & Integrity

  • Features

  • FAQ

The Science of Longevity Starts with NAD+

Aging isn’t just what you see in the mirror—it’s what happens deep inside your cells. At the center of healthy aging lies NAD+ (Nicotinamide Adenine Dinucleotide), a coenzyme your body relies on to generate energy, repair DNA, and regulate essential cellular functions. But NAD+ doesn’t last forever. By middle age, your NAD+ levels may drop by 50% or more. This silent depletion weakens your body’s ability to stay energized, defend itself, and recover—accelerating biological aging.

Why Does NAD+ Decline With Age?

Over time, enzymes like CD38 (a protein that eats up NAD+ as it works) and PARPs (a group of enzymes that use NAD+ to help repair DNA) become more active, consuming large amounts of NAD+. The recycling process that restores NAD+—driven by the enzyme NAMPT (the main enzyme that helps make new NAD+)—slows down. At the same time, chronic inflammation and metabolic stress (problems with how the body uses energy) create an even greater demand. The result is a cellular environment where energy falters, repair slows, and aging accelerates (Schultz & Sinclair, 2016; Covarrubias et al., 2020).

How NMN Rebuilds Your NAD+ Supply!

NMN (Nicotinamide Mononucleotide) is the direct precursor (the raw material your body uses) to create NAD+ through the salvage pathway (the recycling system for NAD+). It’s converted into NAD+ by specialized enzymes known as NMNATs (a group of enzymes that turn NMN into NAD+), which operate in key areas like the nucleus (the control center of the cell), cytosol (the fluid inside cells), and mitochondria (the cell’s energy factories)—ensuring NAD+ is restored exactly where your body needs it most (Hong et al., 2020; Wei et al., 2023; Jeje et al., 2024).

What Happens When NAD+ Is Restored

Cellular Health

Restored NAD+ levels support DNA repair, activate protective longevity genes like SIRT1 (genes that help cells live longer and work better), and reduce oxidative damage (wear-and-tear caused by stress, pollution, and aging)—giving your cells the resilience they need to withstand stress and aging.

Energy & Metabolism

Mitochondria (tiny engines inside your cells) rely on NAD+ to function. With higher NAD+, your body generates energy more efficiently, stabilizes blood sugar, improves insulin sensitivity (how well your body responds to insulin), and burns fuel more effectively (Nadtochiy & Brookes, 2017).

Brain & Neurovascular Function

Increased NAD+ improves blood flow to the brain, enhances neurovascular coupling (how brain cells and blood vessels work together), and protects against age-related cognitive decline. Studies show NMN activates mitochondrial defenses and reduces inflammation in brain and nerve tissue (Kiss et al., 2020; Wang et al., 2016).

Physical Performance & Mobility

Restoring NAD+ helps maintain strength, coordination, and mobility. Clinical research shows NMN improves walking speed, muscle performance, and physical energy in older adults (Kim et al., 2022).

Cardiovascular Health

NAD+ protects the heart and arteries by reducing inflammation, improving endothelial function (how blood vessels expand and contract), and limiting oxidative stress (cell damage from unstable molecules called free radicals). NMN has shown positive effects in slowing atherosclerosis (plaque buildup in the arteries) and protecting vascular health (Wang et al., 2023).

Female Fertility

In aging females, NAD+ depletion impairs egg quality and hormone balance. NMN restores ovarian NAD+ levels, improves mitochondrial function, and helps rejuvenate fertility (Liang et al., 2024; Bertoldo et al., 2020).

Recovery & Resilience

From nerve damage to mitochondrial disorders (conditions where cells can’t make enough energy), NAD+ restoration helps the body bounce back. NMN improves outcomes in spinal cord injury models (animal studies on nerve damage) and boosts survival in mitochondrial disease by reducing toxic cellular byproducts (harmful waste created inside cells) (Zhang et al., 2023).

Immune Support

Higher NAD+ levels strengthen immune response and reduce inflammation. In respiratory models (lab studies on breathing and lung health), NMN has been shown to help fight viral infections and accelerate recovery (Jiang et al., 2022).

Skin Health & Appearance

NMN fuels cellular repair in the skin, improving tone, texture, and elasticity (how firm and flexible your skin is). It supports collagen production (the protein that keeps skin strong and smooth), reduces redness and UV damage, and has shown potential in treating psoriasis (a common inflammatory skin condition) and other skin issues (Kang et al., 2024; Zhang et al., 2024; Betsuno et al., 2025).

Proven Human Results

NMN fuels cellular repair in the skin, improving tone, texture, and elasticity (how firm and flexible your skin is). It supports collagen production (the protein that keeps skin strong and smooth), reduces redness and UV damage, and has shown potential in treating psoriasis (a common inflammatory skin condition) and other skin issues (Okabe et al., 2022; Kimura et al., 2022; Kim et al., 2022).

Why Purity Matters in the Formula

Every published human study showing NMN’s benefits — from energy and metabolism to NAD+ restoration — used the pure form of NMN, not blended or altered versions. Ultra Pure NMN™ delivers over 99% pharmaceutical-grade beta-NMN, precisely matching the form and purity used in clinical research.

Other brands often dilute NMN with cheaper ingredients or hide lower doses in proprietary blends to cut costs. But unproven combinations can compromise absorption and effectiveness. We don’t experiment — we deliver the exact NMN trusted by researchers to elevate NAD+, support longevity, and drive real cellular change.

Why Capsules Still Lead the Way in NMN Delivery

With so many NMN delivery methods on the market—powders, sublinguals, liposomal liquids, lozenges, transdermal patches—why do we still choose Ultra Pure NMN™ in capsule form?

Because the science shows it’s still the most reliable, effective, and convenient method for daily NAD+ support in adults.

Protection from Stomach Breakdown

Free NMN is vulnerable to harsh environments—especially the acidic conditions in your stomach. When unprotected, it can degrade into less effective compounds like nicotinamide. That’s why capsule delivery still leads the way. In a human clinical study, orally administered NMN was rapidly absorbed and safely metabolized, with increased levels of key NMN metabolites detected over five hours—confirming active uptake via the small intestine (Irie et al., 2020). Capsules help ensure NMN survives digestion and reaches its optimal absorption site with minimal waste.

Precise Dosing, Every Time

Each capsule delivers a consistent, pre-measured dose of NMN—no guesswork, no variation. This level of control is critical for replicating the results seen in clinical trials, where doses range from 300mg to 900mg daily. Compared to powders or liquids, capsules offer unmatched precision and dosing simplicity (Stegemann, 2011).

Convenient, Safe, and Travel-Ready

Capsules are easy to take, portable, and clean—no measuring spoons, no bitter taste, no spills. They also protect NMN from exposure to light, moisture, and oxygen, helping to preserve potency and shelf life.

Efficient Absorption Where It Matters Most

HealthspanX Ultra Pure NMN™ capsules are designed to dissolve efficiently in the small intestine—your body’s key site for nutrient uptake. While they don’t use time-release technology, their encapsulated format helps ensure NMN survives stomach acid and reaches its ideal absorption point with high stability and minimal waste.

Backed by Simplicity, Not Gimmicks

While experimental delivery systems like nanoemulsions and microneedles are still being explored, Ultra Pure NMN™ relies on a proven, straightforward approach: high-purity NMN, properly dosed, and delivered in a stable capsule. It’s the same pharmaceutical-grade NMN used in human clinical trials—without unnecessary complexity or unvalidated technologies.

Proven in Human Clinical Studies

Multiple human clinical trials have used oral NMN capsules to safely and effectively raise NAD+ levels. One multicenter, randomized, double-blind study confirmed significant increases in NAD+ in healthy middle-aged adults (Yi et al., 2022). Another trial in older individuals found that NMN capsules improved walking speed, sleep quality, and overall vitality (Morifuji et al., 2024).

Recommended Daily Dosage

Take 2 capsules (500mg total) once daily in the morning.
This is the ideal dose based on published human clinical trials and aligns with how NAD+ production naturally functions in the body.

When to Take It

Take Ultra Pure NMN™ first thing in the morning, preferably at the same time each day.
Morning usage supports your body’s circadian rhythm and mirrors how NAD+ levels fluctuate throughout the day.

How Long to Take It

For lasting results, take Ultra Pure NMN™ daily and consistently. Most people begin to notice benefits in 2 to 4 weeks, with deeper cellular improvements building over 60+ days.

Scientifically Aligned

This protocol is based on peer-reviewed clinical research showing that NMN taken daily can:

  • Increase blood NAD+ levels
  • Improve energy metabolism and mitochondrial function
  • Support physical performance, cognitive clarity, and longevity biomarkers (Morifuji et al., 2024; Wen et al., 2024)

Lab Verified. Clinically Trusted. 100% Transparent.

At HealthspanX, we don’t just claim purity — we prove it. Every batch of Ultra Pure NMN™ undergoes rigorous testing in a certified U.S. laboratory to verify identity, purity, and safety — with results you can trust.

Identity & Potency Confirmed by HPLC

Each capsule contains β-Nicotinamide Mononucleotide (NMN), verified using High-Performance Liquid Chromatography (HPLC) — an advanced method used to confirm the presence, strength, and purity of ingredients.
Certified Purity: Over 99% — exceeding industry benchmarks.

Heavy Metal Testing (ICP-MS)

We use Inductively Coupled Plasma Mass Spectrometry (ICP-MS) — one of the most sensitive techniques available — to detect even trace amounts of toxic metals. Our results are well below global safety thresholds:

  • Arsenic: 0.034 ppm (limit: 0.5 ppm)
  • Cadmium: 0.003 ppm (limit: 0.5 ppm)
  • Mercury: 0.002 ppm (limit: 0.1 ppm)
  • Lead: 0.018 ppm (limit: 0.5 ppm)

Microbial Screening (USP Standards)

Each batch is screened for microbial contamination according to USP (United States Pharmacopeia) standards. These tests ensure the product is free of harmful bacteria, yeast, and mold:

  • Yeast & Mold: <10 cfu/g (safe limit: 100 cfu/g)
  • Coliforms, E. coli, Salmonella, S. aureus, Pseudomonas, Candida: All not detected

Third-Party Lab Integrity You Can Trust

Testing is performed by Certified Laboratories — a U.S.-based, ISO/IEC 17025-accredited facility (Lab Cert 3041.01). This means:

  • Tests meet international scientific standards
  • Each batch is independently verified
  • Full ingredient traceability is guaranteed

This ensures everything inside the capsule is exactly what’s on the label — nothing more, nothing less.

Beware of Fake NMN: Choose Clinical-Grade Purity

Not all NMN is created equal. Some companies flood the market with cheap, low-quality, or even fake NMN to undercut prices. This puts your health at risk and damages the trust in real, science-backed products. At HealthspanX, our Ultra Pure NMN™ is the same pharmaceutical-grade NMN used in human clinical trials—tested for purity, potency, and safety. When it comes to your health and longevity, don't settle for less.

Purity: Over 99% Ultra-Pure NMN

Verified by High-Performance Liquid Chromatography (HPLC) and tested by Certified Laboratories. Our NMN exceeds clinical standards and contains no binders, fillers, or impurities.

Dose: 1000mg NMN Per Daily Serving

Each daily dose (2 capsules) delivers the exact dosage used in human clinical studies — designed to restore NAD+ levels effectively in adults.

Capsules Per Pack: 62 Pharmaceutical-Grade Capsules

One full month of therapeutic-grade NMN. Precision-dosed, easy to swallow, and independently tested for consistency and quality.

Safety Tested: USA Lab-Tested for Heavy Metals & Microbes

Tested using ICP-MS and USP protocols for arsenic, cadmium, mercury, lead, yeast, mold, E. coli, salmonella, and more. All results: Not Detected or Far Below Safety Limits.

Vegan & Clean Formula

Free from dairy, gluten, eggs, soy, wheat, chemicals, solvents, or artificial flavors. 100% vegan-friendly and suitable for daily use.

Certifications: ISO 9001, HACCP, Kosher, and Halal Certified

Manufactured under strict international standards. Every capsule reflects our commitment to purity, safety, and universal accessibility.

3rd-Party Verified

Independently tested for purity, potency, and identity — with full COA (Certificate of Analysis) available on request.

Eco-Packaged: Sustainable Sachets, Not Plastic Bottles

We use recyclable, low-impact sachets instead of bulky plastic bottles — reducing waste and minimizing our environmental footprint without compromising product integrity. Better for the planet, safer for you.

What Is NMN and How Does It Work?

NMN (Nicotinamide Mononucleotide) is a direct precursor (the raw material your body uses) to NAD+, a critical molecule that powers cellular energy production and activates enzymes involved in longevity and health maintenance. As we age, NAD+ levels decline significantly, and NMN supplementation helps restore these levels by providing the raw material your body needs to synthesize NAD+.

How Should I Take Ultra Pure NMN™? 

For optimal results, take two 500mg capsules daily, preferably in the morning with or without food. Some users report enhanced benefits when taken on an empty stomach.

How Long Before I Notice Results?

Most users report initial improvements in energy levels within 2-3 weeks of consistent use. More comprehensive benefits to cognitive function, exercise recovery, and overall vitality typically become apparent after 1-2 months of regular supplementation.

Is Ultra Pure NMN™ Safe to Take with Other Supplements or Medications?

Ultra Pure NMN™ is designed to complement most health regimens. It pairs exceptionally well with our Resveratrol and Quercetin supplements for enhanced NAD+ support. If you're taking prescription medications or have underlying health conditions, we recommend consulting with your healthcare provider before beginning supplementation.

What Age Should I Start Taking NMN?

NAD+ levels begin declining in your late 20s and drop sharply by your 40s. Supplementing with NMN is beneficial for anyone seeking to maintain cellular energy, support healthy aging, and optimize metabolic function—especially from age 35 onward. Those in their 50s and 60s often notice more pronounced effects in energy, clarity, and recovery.

Does Ultra Pure NMN™ Have Side Effects?

The available human clinical trials consistently show that Ultra Pure NMN™ (Same NMN used in Clinical Trials) is safe and well-tolerated in healthy adults, with no serious side effects reported across a range of doses and durations.
 

Safety and Tolerability

  • Multiple randomized, placebo-controlled trials found that daily oral NMN supplementation—ranging up to 1250 mg per day—did not result in significant adverse effects or abnormal changes in physiological, laboratory, or clinical parameters in healthy adults. 
  • No severe adverse events were observed, and reported side effects were rare and not directly linked to NMN supplementation. 

Dosage

  • Studies tested a wide range of NMN doses (up to 1250 mg daily) and found all to be safe.
  • Even at the higher doses, NMN was well-tolerated with no significant safety concerns.

What Is the Right Dosage for Me?

To find the right NMN dosage for you, here’s what current research suggests:


Evidence:

  • Common effective range: Studies generally used doses between 500 mg and 1000 mg per day in adults aged 20–65 years, finding significant benefits like increased NAD+ levels, improved physical performance, and better overall health without side effects.
  • Best results around 1000 mg/day: Several trials showed that 1000 mg per day seems to offer the strongest boost in NAD+ and physical function improvements, especially for middle-aged adults.
  • Personal variability: Some people show greater NAD+ increases than others at the same dose, suggesting it might be helpful to start lower (around 500) and adjust based on how you feel and your goals.

Special Cases:

If you are older (60+) or have specific health goals like boosting fertility, improving metabolic health, or combating aging signs, you might lean toward higher doses.

Is Ultra Pure NMN™ Vegan and Allergen-Free?

Yes. Our capsules are plant-based, and our formula contains no animal products, gluten, dairy, soy, or artificial additives. Ultra Pure NMN™ is 100% vegan, non-GMO, and formulated for purity, safety, and simplicity.

How Should I Store Ultra Pure NMN™?

Store in a cool, dry place away from direct sunlight. No refrigeration is needed. Our moisture-resistant sachet packaging ensures maximum stability and purity over time.

Do You Offer a Subscription Option?

Yes. HealthspanX offers a flexible bimonthly subscription of Ultra Pure NMN™. You'll enjoy 15% off regular pricing, automatic deliveries, and the freedom to skip, pause, or cancel anytime—ensuring you never run out.

Science

The Science of Longevity Starts with NAD+

Aging isn’t just what you see in the mirror—it’s what happens deep inside your cells. At the center of healthy aging lies NAD+ (Nicotinamide Adenine Dinucleotide), a coenzyme your body relies on to generate energy, repair DNA, and regulate essential cellular functions. But NAD+ doesn’t last forever. By middle age, your NAD+ levels may drop by 50% or more. This silent depletion weakens your body’s ability to stay energized, defend itself, and recover—accelerating biological aging.

Why Does NAD+ Decline With Age?

Over time, enzymes like CD38 (a protein that eats up NAD+ as it works) and PARPs (a group of enzymes that use NAD+ to help repair DNA) become more active, consuming large amounts of NAD+. The recycling process that restores NAD+—driven by the enzyme NAMPT (the main enzyme that helps make new NAD+)—slows down. At the same time, chronic inflammation and metabolic stress (problems with how the body uses energy) create an even greater demand. The result is a cellular environment where energy falters, repair slows, and aging accelerates (Schultz & Sinclair, 2016; Covarrubias et al., 2020).

How NMN Rebuilds Your NAD+ Supply!

NMN (Nicotinamide Mononucleotide) is the direct precursor (the raw material your body uses) to create NAD+ through the salvage pathway (the recycling system for NAD+). It’s converted into NAD+ by specialized enzymes known as NMNATs (a group of enzymes that turn NMN into NAD+), which operate in key areas like the nucleus (the control center of the cell), cytosol (the fluid inside cells), and mitochondria (the cell’s energy factories)—ensuring NAD+ is restored exactly where your body needs it most (Hong et al., 2020; Wei et al., 2023; Jeje et al., 2024).

What Happens When NAD+ Is Restored

Cellular Health

Restored NAD+ levels support DNA repair, activate protective longevity genes like SIRT1 (genes that help cells live longer and work better), and reduce oxidative damage (wear-and-tear caused by stress, pollution, and aging)—giving your cells the resilience they need to withstand stress and aging.

Energy & Metabolism

Mitochondria (tiny engines inside your cells) rely on NAD+ to function. With higher NAD+, your body generates energy more efficiently, stabilizes blood sugar, improves insulin sensitivity (how well your body responds to insulin), and burns fuel more effectively (Nadtochiy & Brookes, 2017).

Brain & Neurovascular Function

Increased NAD+ improves blood flow to the brain, enhances neurovascular coupling (how brain cells and blood vessels work together), and protects against age-related cognitive decline. Studies show NMN activates mitochondrial defenses and reduces inflammation in brain and nerve tissue (Kiss et al., 2020; Wang et al., 2016).

Physical Performance & Mobility

Restoring NAD+ helps maintain strength, coordination, and mobility. Clinical research shows NMN improves walking speed, muscle performance, and physical energy in older adults (Kim et al., 2022).

Cardiovascular Health

NAD+ protects the heart and arteries by reducing inflammation, improving endothelial function (how blood vessels expand and contract), and limiting oxidative stress (cell damage from unstable molecules called free radicals). NMN has shown positive effects in slowing atherosclerosis (plaque buildup in the arteries) and protecting vascular health (Wang et al., 2023).

Female Fertility

In aging females, NAD+ depletion impairs egg quality and hormone balance. NMN restores ovarian NAD+ levels, improves mitochondrial function, and helps rejuvenate fertility (Liang et al., 2024; Bertoldo et al., 2020).

Recovery & Resilience

From nerve damage to mitochondrial disorders (conditions where cells can’t make enough energy), NAD+ restoration helps the body bounce back. NMN improves outcomes in spinal cord injury models (animal studies on nerve damage) and boosts survival in mitochondrial disease by reducing toxic cellular byproducts (harmful waste created inside cells) (Zhang et al., 2023).

Immune Support

Higher NAD+ levels strengthen immune response and reduce inflammation. In respiratory models (lab studies on breathing and lung health), NMN has been shown to help fight viral infections and accelerate recovery (Jiang et al., 2022).

Skin Health & Appearance

NMN fuels cellular repair in the skin, improving tone, texture, and elasticity (how firm and flexible your skin is). It supports collagen production (the protein that keeps skin strong and smooth), reduces redness and UV damage, and has shown potential in treating psoriasis (a common inflammatory skin condition) and other skin issues (Kang et al., 2024; Zhang et al., 2024; Betsuno et al., 2025).

Proven Human Results

NMN fuels cellular repair in the skin, improving tone, texture, and elasticity (how firm and flexible your skin is). It supports collagen production (the protein that keeps skin strong and smooth), reduces redness and UV damage, and has shown potential in treating psoriasis (a common inflammatory skin condition) and other skin issues (Okabe et al., 2022; Kimura et al., 2022; Kim et al., 2022).

Formula

Why Purity Matters in the Formula

Every published human study showing NMN’s benefits — from energy and metabolism to NAD+ restoration — used the pure form of NMN, not blended or altered versions. Ultra Pure NMN™ delivers over 99% pharmaceutical-grade beta-NMN, precisely matching the form and purity used in clinical research.

Other brands often dilute NMN with cheaper ingredients or hide lower doses in proprietary blends to cut costs. But unproven combinations can compromise absorption and effectiveness. We don’t experiment — we deliver the exact NMN trusted by researchers to elevate NAD+, support longevity, and drive real cellular change.

Why Capsules Still Lead the Way in NMN Delivery

With so many NMN delivery methods on the market—powders, sublinguals, liposomal liquids, lozenges, transdermal patches—why do we still choose Ultra Pure NMN™ in capsule form?

Because the science shows it’s still the most reliable, effective, and convenient method for daily NAD+ support in adults.

Protection from Stomach Breakdown

Free NMN is vulnerable to harsh environments—especially the acidic conditions in your stomach. When unprotected, it can degrade into less effective compounds like nicotinamide. That’s why capsule delivery still leads the way. In a human clinical study, orally administered NMN was rapidly absorbed and safely metabolized, with increased levels of key NMN metabolites detected over five hours—confirming active uptake via the small intestine (Irie et al., 2020). Capsules help ensure NMN survives digestion and reaches its optimal absorption site with minimal waste.

Precise Dosing, Every Time

Each capsule delivers a consistent, pre-measured dose of NMN—no guesswork, no variation. This level of control is critical for replicating the results seen in clinical trials, where doses range from 300mg to 900mg daily. Compared to powders or liquids, capsules offer unmatched precision and dosing simplicity (Stegemann, 2011).

Convenient, Safe, and Travel-Ready

Capsules are easy to take, portable, and clean—no measuring spoons, no bitter taste, no spills. They also protect NMN from exposure to light, moisture, and oxygen, helping to preserve potency and shelf life.

Efficient Absorption Where It Matters Most

HealthspanX Ultra Pure NMN™ capsules are designed to dissolve efficiently in the small intestine—your body’s key site for nutrient uptake. While they don’t use time-release technology, their encapsulated format helps ensure NMN survives stomach acid and reaches its ideal absorption point with high stability and minimal waste.

Backed by Simplicity, Not Gimmicks

While experimental delivery systems like nanoemulsions and microneedles are still being explored, Ultra Pure NMN™ relies on a proven, straightforward approach: high-purity NMN, properly dosed, and delivered in a stable capsule. It’s the same pharmaceutical-grade NMN used in human clinical trials—without unnecessary complexity or unvalidated technologies.

Proven in Human Clinical Studies

Multiple human clinical trials have used oral NMN capsules to safely and effectively raise NAD+ levels. One multicenter, randomized, double-blind study confirmed significant increases in NAD+ in healthy middle-aged adults (Yi et al., 2022). Another trial in older individuals found that NMN capsules improved walking speed, sleep quality, and overall vitality (Morifuji et al., 2024).

Usage

Recommended Daily Dosage

Take 2 capsules (500mg total) once daily in the morning.
This is the ideal dose based on published human clinical trials and aligns with how NAD+ production naturally functions in the body.

When to Take It

Take Ultra Pure NMN™ first thing in the morning, preferably at the same time each day.
Morning usage supports your body’s circadian rhythm and mirrors how NAD+ levels fluctuate throughout the day.

How Long to Take It

For lasting results, take Ultra Pure NMN™ daily and consistently. Most people begin to notice benefits in 2 to 4 weeks, with deeper cellular improvements building over 60+ days.

Scientifically Aligned

This protocol is based on peer-reviewed clinical research showing that NMN taken daily can:

  • Increase blood NAD+ levels
  • Improve energy metabolism and mitochondrial function
  • Support physical performance, cognitive clarity, and longevity biomarkers (Morifuji et al., 2024; Wen et al., 2024)

Lab Testing & Integrity

Lab Verified. Clinically Trusted. 100% Transparent.

At HealthspanX, we don’t just claim purity — we prove it. Every batch of Ultra Pure NMN™ undergoes rigorous testing in a certified U.S. laboratory to verify identity, purity, and safety — with results you can trust.

Identity & Potency Confirmed by HPLC

Each capsule contains β-Nicotinamide Mononucleotide (NMN), verified using High-Performance Liquid Chromatography (HPLC) — an advanced method used to confirm the presence, strength, and purity of ingredients.
Certified Purity: Over 99% — exceeding industry benchmarks.

Heavy Metal Testing (ICP-MS)

We use Inductively Coupled Plasma Mass Spectrometry (ICP-MS) — one of the most sensitive techniques available — to detect even trace amounts of toxic metals. Our results are well below global safety thresholds:

  • Arsenic: 0.034 ppm (limit: 0.5 ppm)
  • Cadmium: 0.003 ppm (limit: 0.5 ppm)
  • Mercury: 0.002 ppm (limit: 0.1 ppm)
  • Lead: 0.018 ppm (limit: 0.5 ppm)

Microbial Screening (USP Standards)

Each batch is screened for microbial contamination according to USP (United States Pharmacopeia) standards. These tests ensure the product is free of harmful bacteria, yeast, and mold:

  • Yeast & Mold: <10 cfu/g (safe limit: 100 cfu/g)
  • Coliforms, E. coli, Salmonella, S. aureus, Pseudomonas, Candida: All not detected

Third-Party Lab Integrity You Can Trust

Testing is performed by Certified Laboratories — a U.S.-based, ISO/IEC 17025-accredited facility (Lab Cert 3041.01). This means:

  • Tests meet international scientific standards
  • Each batch is independently verified
  • Full ingredient traceability is guaranteed

This ensures everything inside the capsule is exactly what’s on the label — nothing more, nothing less.

Beware of Fake NMN: Choose Clinical-Grade Purity

Not all NMN is created equal. Some companies flood the market with cheap, low-quality, or even fake NMN to undercut prices. This puts your health at risk and damages the trust in real, science-backed products. At HealthspanX, our Ultra Pure NMN™ is the same pharmaceutical-grade NMN used in human clinical trials—tested for purity, potency, and safety. When it comes to your health and longevity, don't settle for less.

Features

Purity: Over 99% Ultra-Pure NMN

Verified by High-Performance Liquid Chromatography (HPLC) and tested by Certified Laboratories. Our NMN exceeds clinical standards and contains no binders, fillers, or impurities.

Dose: 1000mg NMN Per Daily Serving

Each daily dose (2 capsules) delivers the exact dosage used in human clinical studies — designed to restore NAD+ levels effectively in adults.

Capsules Per Pack: 62 Pharmaceutical-Grade Capsules

One full month of therapeutic-grade NMN. Precision-dosed, easy to swallow, and independently tested for consistency and quality.

Safety Tested: USA Lab-Tested for Heavy Metals & Microbes

Tested using ICP-MS and USP protocols for arsenic, cadmium, mercury, lead, yeast, mold, E. coli, salmonella, and more. All results: Not Detected or Far Below Safety Limits.

Vegan & Clean Formula

Free from dairy, gluten, eggs, soy, wheat, chemicals, solvents, or artificial flavors. 100% vegan-friendly and suitable for daily use.

Certifications: ISO 9001, HACCP, Kosher, and Halal Certified

Manufactured under strict international standards. Every capsule reflects our commitment to purity, safety, and universal accessibility.

3rd-Party Verified

Independently tested for purity, potency, and identity — with full COA (Certificate of Analysis) available on request.

Eco-Packaged: Sustainable Sachets, Not Plastic Bottles

We use recyclable, low-impact sachets instead of bulky plastic bottles — reducing waste and minimizing our environmental footprint without compromising product integrity. Better for the planet, safer for you.

FAQ

What Is NMN and How Does It Work?

NMN (Nicotinamide Mononucleotide) is a direct precursor to NAD+, a critical molecule that powers cellular energy production and activates enzymes involved in longevity and health maintenance. As we age, NAD+ levels decline significantly, and NMN supplementation helps restore these levels by providing the raw material your body needs to synthesize NAD+.

How Should I Take Ultra Pure NMN™? 

For optimal results, take two 500mg capsules daily, preferably in the morning with or without food. Some users report enhanced benefits when taken on an empty stomach.

How Long Before I Notice Results?

Most users report initial improvements in energy levels within 2-3 weeks of consistent use. More comprehensive benefits to cognitive function, exercise recovery, and overall vitality typically become apparent after 1-2 months of regular supplementation.

Is Ultra Pure NMN™ Safe to Take with Other Supplements or Medications?

Ultra Pure NMN™ is designed to complement most health regimens. It pairs exceptionally well with our Resveratrol and Quercetin supplements for enhanced NAD+ support. If you're taking prescription medications or have underlying health conditions, we recommend consulting with your healthcare provider before beginning supplementation.

What Age Should I Start Taking NMN?

NAD+ levels begin declining in your late 20s and drop sharply by your 40s. Supplementing with NMN is beneficial for anyone seeking to maintain cellular energy, support healthy aging, and optimize metabolic function—especially from age 35 onward. Those in their 50s and 60s often notice more pronounced effects in energy, clarity, and recovery.

Does Ultra Pure NMN™ Have Side Effects?

The available human clinical trials consistently show that Ultra Pure NMN™ (Same NMN used in Clinical Trials) is safe and well-tolerated in healthy adults, with no serious side effects reported across a range of doses and durations.
 

Safety and Tolerability

  • Multiple randomized, placebo-controlled trials found that daily oral NMN supplementation—ranging up to 1250 mg per day—did not result in significant adverse effects or abnormal changes in physiological, laboratory, or clinical parameters in healthy adults. 
  • No severe adverse events were observed, and reported side effects were rare and not directly linked to NMN supplementation. 

Dosage

  • Studies tested a wide range of NMN doses (up to 1250 mg daily) and found all to be safe.
  • Even at the higher doses, NMN was well-tolerated with no significant safety concerns.

What Is the Right Dosage for Me?

To find the right NMN dosage for you, here’s what current research suggests:


Evidence:

  • Common effective range: Studies generally used doses between 500 mg and 1000 mg per day in adults aged 20–65 years, finding significant benefits like increased NAD+ levels, improved physical performance, and better overall health without side effects.
  • Best results around 1000 mg/day: Several trials showed that 1000 mg per day seems to offer the strongest boost in NAD+ and physical function improvements, especially for middle-aged adults.
  • Personal variability: Some people show greater NAD+ increases than others at the same dose, suggesting it might be helpful to start lower (around 500) and adjust based on how you feel and your goals.

Special cases:

If you are older (60+) or have specific health goals like boosting fertility, improving metabolic health, or combating aging signs, you might lean toward higher doses.

Is Ultra Pure NMN™ Vegan and Allergen-Free?

Yes. Our capsules are plant-based, and our formula contains no animal products, gluten, dairy, soy, or artificial additives. Ultra Pure NMN™ is 100% vegan, non-GMO, and formulated for purity, safety, and simplicity.

How Should I Store Ultra Pure NMN™?

Store in a cool, dry place away from direct sunlight. No refrigeration is needed. Our moisture-resistant sachet packaging ensures maximum stability and purity over time.

Do You Offer a Subscription Option?

Yes. HealthspanX offers a flexible bimonthly subscription of Ultra Pure NMN™. You'll enjoy 15% off regular pricing, automatic deliveries, and the freedom to skip, pause, or cancel anytime—ensuring you never run out.

Feel the Difference in Just Weeks — Experience Better Energy, Focus, & Cellular Vitality

Ultra Pure NMN™ helps replenish your body's NAD+ levels; a key factor in how fast (or slow) you age. Within weeks, users report noticeable improvements in energy, focus, skin, and overall vitality.

Enhanced Energy

Boost NAD+ levels for optimal cellular energy production and mitochondrial function, helping combat age-related fatigue and restore youthful vitality at the cellular level.

Cognitive Support

Improve focus, mental clarity and cognitive performance by supporting brain cell health and enhancing neuronal NAD+ levels crucial for optimal brain function.

Cardiovascular Health

Support healthy blood vessels and heart function through improved vascular endothelial cell function and enhanced blood flow regulation.

Skin Health

Support smoother, more radiant skin by improving cellular repair and hydration at the deepest levels. Boosts NAD+ to help reduce the visible signs of aging and promote a youthful glow from within.

Longevity Support 

Activate longevity pathways and support DNA repair mechanisms that naturally decline with age, promoting cellular resilience and healthier aging.

These are just a few of the powerful effects. In our NMN science section, you’ll discover even more clinically studied benefits — including enhanced metabolism, immune system strength, sleep quality, and cellular protection. See how NMN supports your body from the inside out.

99% Customers Are Satisfied

What Verified Customers Are Saying About Ultra Pure NMN™

No More Afternoon Slumps—Sharper Focus & All-Day Energy

After two months of taking NMN, I've noticed a remarkable change in my energy levels. I'm able to get through my entire day without the usual afternoon slump. My mental clarity has improved significantly too! I'm remembering details better and feel more focused at work.

Terry Y.

  • Verified Buyer

Faster Recovery, More Energy, and Surprisingly Better Sleep

As someone who works out regularly, I've noticed significantly improved recovery time since starting NMN. My muscle soreness doesn't last nearly as long, and I have more energy during workouts. What surprised me most was how much better my sleep quality has become.

Lynda H.

  • Verified Buyer

At 63, I Feel Recharged—Energy, Immunity & a Boosted Routine

At 63, I was starting to feel my age. Since taking NMN, my energy levels have significantly improved, and I haven't gotten sick once this winter! My wife has noticed the difference and just started taking it too. Thanks, HealthspanX. Keep up the good work! 

Mark R.

  • Verified Buyer

Complete Your NAD+ Support Regimen

Amplify Your NMN Results with Ultra Pure Resveratrol™ & Ultra Pure Quercetin™

Ultra Pure Resveratrol™ activates sirtuin genes to enhance NMN efficacy and optimize NAD+ production for longevity.  Ultra Pure Quercetin™ acts as a potent senolytic, clearing aging cells and boosting NAD+ benefits while supporting immune health. 

Together, they amplify NMN's impact on cellular vitality and healthy aging.

HealthspanX 60-Day Confidence Guarantee

We stand behind Ultra Pure NMN™ with a no-hassle 60-day money-back guarantee. If you're not satisfied for any reason, we’ll make it right—quickly and easily through our Return Portal.

Why so confident? Because our NMN is the same pharmaceutical-grade compound used in human clinical trials—tested, verified, and trusted. For more information, please check our Return and Refund Policy.

Why Choose HealthspanX?

Where Clinical-Grade Purity Meets Purpose

HealthspanX was founded by a visionary whose life was transformed by NMN and the science of NAD+ restoration. What began as a personal breakthrough became a mission to bring clarity, credibility, and clinical-grade solutions to those serious about aging well.

 

We don’t chase trends—we deliver evidence. Our Ultra Pure NMN™ is the same pharmaceutical-grade ingredient used in human clinical trials, verified for 99%+ purity and tested by third-party U.S. labs. Every formula is backed by research, not marketing.

 

At HealthspanX, we translate complex longevity science into real-world results—without the hype, the guesswork, or the waste. Because longevity isn’t a trend. It’s your future, and we’re here to help you protect it.

Have a Question or Need Support? 

The HealthspanX team is ready to help with fast, personalized assistance.
📩 Email us anytime at support@healthspanx.org — we typically respond within 24 hours.

Subscribe to Our Newsletter

Sign up to be the first to hear about longevity tips, exclusive deals, and special offers.