Formulated by Science. Verified by Labs. Trusted by Longevity Seekers.

Same Trans-Resveratrol Trusted in Longevity Research
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules

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US orders over $50 and international over $100 

Money-Back Guarantee

Peace of mind with our 60-day money-back guarantee.

The HealthspanX Standard™
Where Clinical Purity Meets Real-World Results

At HealthspanX, we don’t follow trends — we follow the science. Our Ultra Pure Resveratrol™ is pharmaceutical-grade, third-party tested, and exceeds 101% purity — the same standard used in clinical research. No fillers. No gimmicks. Just clean, high-potency resveratrol to support your heart, brain, and cellular health from the inside out. Trusted by professionals. Backed by science. Designed for results.
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules
Ultra Pure Resveratrol™ 500mg, 62 Capsules

Based on Verified Customers

Ultra Pure Resveratrol™ 500mg, 62 Capsules

As we age, oxidative stress, inflammation, and cellular decline accelerate, impacting heart health, brain function, and overall vitality. Ultra Pure Resveratrol™ is clinically formulated to defend against these changes by supporting SIRT1 activation, mitochondrial function, and powerful antioxidant protection.

Experience better circulation, cognitive clarity, healthy inflammation response, and lasting cellular wellness — all from the inside out. Whether you're aging proactively or looking to strengthen your core systems, Ultra Pure Resveratrol™ is your trusted daily defense.
$45.00
$0.00

Delivery Size - Daily Dosage

The HealthspanX Standard™
Where Clinical Purity Meets Real-World Results

At HealthspanX, we don’t follow trends — we follow the science. Our Ultra Pure Resveratrol™ is pharmaceutical-grade, third-party tested, and exceeds 101% purity — the same standard used in clinical research. No fillers. No gimmicks. Just clean, high-potency resveratrol to support your heart, brain, and cellular health from the inside out. Trusted by professionals. Backed by science. Designed for results.

  • Science

  • Formula

  • Usage

  • Lab Testing & Integrity

  • Features

  • FAQ

The Science of Healthy Aging Begins with Resveratrol

Resveratrol, a naturally occurring polyphenol (a plant compound with powerful health effects) found in grapes, berries, and red wine, supports healthy aging by acting on multiple cellular pathways. It activates longevity genes (genes that help cells live longer and stay healthier), improves mitochondrial performance (how well your cells make energy), reduces inflammation, and boosts antioxidant defenses (your body’s ability to fight off harmful molecules that damage cells). These interconnected effects make resveratrol a cornerstone of cellular health and a powerful tool in the fight against age-related decline. In simple terms, resveratrol helps your cells stay young, strong, and full of energy (Ungurianu et al., 2023; Kim et al., 2018).

SIRT1 Activation: Turning On Your Longevity Genes

Resveratrol directly activates SIRT1, a critical protein in the sirtuin family (proteins that help your cells age more slowly) that regulates metabolism, DNA repair, and cellular stress response. SIRT1 is an NAD+-dependent enzyme (it needs NAD+, a natural molecule in your body, to work properly). Resveratrol increases NAD+ availability indirectly by activating AMPK (a master switch that helps your cells make and use energy) and upregulating NAMPT, the rate-limiting enzyme (the slowest step in NAD+ recycling) in the NAD+ salvage pathway (your body’s system for reusing NAD+). This enhances SIRT1’s deacetylase activity (its ability to control which genes turn on and off) and amplifies its longevity-promoting effects. Together, this helps your body stay energized, youthful, and better able to repair itself (Grant, 2010; Lan et al., 2017; Peng et al., 2024; Chen et al., 2020).

Powering Up the Mitochondria

Aging is strongly linked to declining mitochondrial efficiency (your cells’ ability to make energy). Resveratrol boosts mitochondrial biogenesis (the creation of new energy-making structures in your cells) through SIRT1’s activation of PGC-1α, a master regulator of mitochondrial growth and function (a protein that tells your cells to make more and better mitochondria). This leads to increased ATP (the main energy unit in your body) and a decrease in damaging reactive oxygen species (ROS) (harmful molecules that can hurt cells), improving overall metabolic function and endurance. That means your body can produce more energy and feel less tired. (Price et al., 2012; Zhang et al., 2024).

Stronger Antioxidant Defenses with NRF2

Resveratrol enhances the body’s antioxidant capacity (its ability to protect against cell damage) by activating NRF2, a transcription factor (a protein that tells your genes what to do) that regulates antioxidant enzymes like SOD, catalase, and glutathione peroxidase (natural chemicals that defend your cells). These enzymes neutralize free radicals (unstable molecules that cause aging and damage), reducing oxidative stress, a major driver of cellular aging. In simple words, this helps your body clean up harmful stuff before it causes damage (Tufekci et al., 2021; Zhang et al., 2024). 

Fighting Inflammaging with NF-κB Modulation

Chronic inflammation, or "inflammaging" (slow, silent swelling inside the body as you age), is a hallmark of aging and age-related disease. Resveratrol helps suppress NF-κB, a pro-inflammatory signaling pathway (a chain reaction in the body that causes inflammation) that triggers cytokines like TNF-α and IL-6 (chemicals that increase swelling and pain). By calming this inflammatory storm, resveratrol helps protect tissues from long-term damage and contributes to heart, brain, and immune health. That means it helps cool down inflammation that could otherwise wear your body out faster (Csiszar, 2011; Iweala et al., 2024).

AMPK: The Master Metabolic Switch

Resveratrol also activates AMPK, the energy sensor of the cell (a protein that monitors your energy levels), which helps regulate metabolism, promote autophagy (a natural way your body cleans up old and damaged parts of cells), and increase mitochondrial health. AMPK and SIRT1 work together to boost cellular resilience (your body’s ability to bounce back from stress) and longevity. Together, they help your body run better, clean itself up, and stay younger longer (Salminen & Kaarniranta, 2012; Ido et al., 2015).

NAD+ Support: Fueling the Engine of Cellular Health

NAD+ (short for Nicotinamide Adenine Dinucleotide) is an essential molecule your cells use for energy production, DNA repair, and activating longevity-related proteins like SIRT1. Resveratrol indirectly boosts NAD+ levels by activating AMPK and increasing the expression of NAMPT (a key enzyme that helps rebuild NAD+), part of the NAD+ salvage pathway (your body’s NAD+ recycling system). Higher NAD+ levels enhance mitochondrial function, reduce oxidative damage, and improve overall metabolic resilience—benefits closely tied to resveratrol’s anti-aging effects. Think of NAD+ like fuel for your body’s repair and energy systems—and resveratrol helps you make more of it.

Real Health Benefits, Backed by Research

Cardiovascular Health

Resveratrol lowers blood pressure, improves cholesterol balance, and protects arteries from oxidative damage and plaque buildup (the sticky stuff that clogs arteries) (Das & Das, 2010; Carrizzo et al., 2013).

Metabolic Regulation

It improves insulin sensitivity (how well your body responds to insulin) and glucose metabolism, mimicking the effects of calorie restriction (eating less to stay healthy and live longer) to support healthy weight and blood sugar control (Pollack et al., 2013).

Brain Health

Resveratrol crosses the blood-brain barrier (it can enter the brain and work there) and protects neurons (brain cells) by reducing inflammation and oxidative damage. Studies show enhanced memory, mood, and cognitive resilience in aging brains (Quincozes‐Santos et al., 2011; Cao et al., 2018).

Immune Modulation

It enhances both innate and adaptive immunity (your fast and slow immune responses) while reducing chronic inflammation, helping the body respond better to infections and slow immune aging (Alesci et al., 2022).

Skin & Hormonal Support

Its antioxidant effects may benefit skin tone and texture, while its ability to interact with estrogen receptors (parts of the body that respond to the female hormone estrogen) shows promise in improving hormonal balance in postmenopausal women (Shin et al., 2015).

Human-Proven Safety with Ultra Pure Resveratrol™

Resveratrol is generally safe and well-tolerated, with over 240 clinical trials studying its impact. Our Resveratrol is ultra-pure, third-party tested, and formulated for maximum safety and performance, delivering exactly what your cells need without unnecessary fillers or contaminants.

Why Purity Matters in the Formula

The clinical benefits of resveratrol — from cardiovascular support to cellular longevity — have only been shown using pure trans-resveratrol, not proprietary blends or diluted extracts. That’s why Ultra Pure Resveratrol™ delivers over 101% tested purity of pharmaceutical-grade trans-resveratrol, with nothing else added.

Many brands cut costs by using low-purity powders or combining resveratrol with unrelated ingredients in a proprietary formula. But there’s no clinical evidence behind those shortcuts. We use only what’s proven — the exact form and purity trusted in human research — so you get results that are real, measurable, and aligned with science.

Why Capsules Still Lead the Way in Resveratrol Delivery

With powders, liquids, lozenges, and even sprays on the market, why do we still choose Ultra Pure Resveratrol™ in capsule form?
Because the science shows it’s the most protective, practical, and clinically relevant method for delivering resveratrol where it matters most—your bloodstream.

Protection from Breakdown in the Stomach

Trans-resveratrol, the active form, is sensitive to stomach acid and prone to degradation before it gets absorbed. Unprotected, it can isomerize or break down into less effective compounds (Koga et al., 2015; Tian & Liu, 2019). Capsules help shield resveratrol from this harsh environment, preserving its potency until it reaches the small intestine—where nutrient absorption actually happens (Walle, 2011; Friend, 2004).

Designed for Absorption Where It Works

The small intestine is the primary site where resveratrol is absorbed via passive diffusion (Walle, 2011). Our encapsulated formula helps ensure that more of the active compound survives digestion and reaches this absorption site, enhancing your chances of getting measurable benefits.

Low Bioavailability, Smart Delivery

Even though about 75% of resveratrol may be absorbed, less than 1% reaches the bloodstream due to rapid breakdown in the liver and gut (Walle, 2011). That’s why delivery matters. Capsule-based strategies—especially when using stable forms like trans-resveratrol—can improve systemic absorption without relying on experimental delivery systems (Briskey & Rao, 2020; Augustin et al., 2013).

Precise Dosing, Every Time

Each Ultra Pure Resveratrol™ capsule contains a consistent 500mg dose—the same purity and precision used in human clinical studies (Sokurenko et al., 2019; Smoliga & Blanchard, 2014). Powders and liquids may vary from dose to dose, but capsules offer predictability—critical for replicating clinical outcomes.

Easy, Portable, and Protected

Capsules are convenient, mess-free, and protect resveratrol from light, air, and moisture—three environmental factors that can degrade potency fast (Pezet et al., 1994; Juškaitė et al., 2017). This protection extends shelf life and helps preserve bioactivity from manufacture to the moment you take it.

Proven in Human Clinical Studies

Resveratrol capsules have been used in numerous human trials studying cardiovascular, anti-aging, and metabolic benefits. Although resveratrol’s bioavailability is naturally low, trials using oral capsules still show promising outcomes—especially when supported by smart formulation and consistent intake (Mohammadi-Sartang et al., 2017; Reis et al., 2024; Smoliga et al., 2011).

No Gimmicks—Just Science

While some companies chase trendy delivery systems like sprays or nano-mist formulations, Ultra Pure Resveratrol™ sticks to what works: a high-purity, properly dosed capsule backed by research. It’s a science-first approach that respects your body—and your wallet.

Recommended Daily Dosage

Take 2 capsules (500mg total) once daily with or without food.
This dosage reflects amounts used in human clinical trials and is consistent with studies showing benefits for cardiovascular, metabolic, and cognitive health.

When to Take It

Take Ultra Pure Resveratrol™ in the morning or with your first meal of the day.
Morning intake aligns with resveratrol’s impact on cellular energy, antioxidant defense, and inflammatory signaling, which follow a circadian rhythm.

How Long to Take It

Take Ultra Pure Resveratrol™ daily and consistently. Most users begin to feel improvements in energy, clarity, or well-being within 2–4 weeks. Clinical studies show more profound effects—including cardiovascular and cognitive benefits—emerge after 8 to 12 weeks of consistent use.

Scientifically Aligned

This protocol is informed by peer-reviewed research showing that daily resveratrol supplementation can:

  • Activate SIRT1 and AMPK pathways involved in longevity and metabolism
  • Improve vascular health, cholesterol profiles, and glucose regulation
  • Cross the blood-brain barrier to support cognitive resilience and reduce neuroinflammation

These benefits are supported by published studies in both clinical and preclinical settings (Cao et al., 2018; Pollack et al., 2013; Das & Das, 2010; Quincozes-Santos et al., 2011).

Lab Verified. Clinically Trusted. 100% Transparent.

At HealthspanX, we don’t just claim purity — we prove it. Every batch of Ultra Pure Resveratrol™ undergoes rigorous third-party testing in a certified U.S. laboratory to verify identity, potency, and safety — with results you can trust.

Identity & Potency Confirmed by UPLC-DAD

Each capsule contains Trans-Resveratrol (500mg), verified using Ultra Performance Liquid Chromatography with Diode Array Detection (UPLC-DAD) — a gold-standard method for confirming ingredient identity and purity.

Tested Purity: Over 101% — comfortably within USP specification (99–102%)

Heavy Metal Testing (USP 233 Protocol Detecting Elemental Impurities)

We screen for heavy metals using validated methodologies to ensure your safety.
Our latest batch results were well below global safety thresholds:

  • Arsenic (As): ND (<2 ppm limit)
  • Cadmium (Cd): ND (<1 ppm limit)
  • Lead (Pb): ND (<2 ppm limit)
  • Mercury (Hg): ND (<0.1 ppm limit)

(ND = Not Detected above reporting threshold)

Microbial Screening (USP Standards)

Each batch is tested for microbial contamination in accordance with USP 2021 and USP 2022 standards to ensure it is safe and clean:

  • Total Yeast & Mold: <100 CFU/g
  • Total Aerobic Plate Count: <100 CFU/g
  • E. coli, Salmonella, Staphylococcus aureus: Not Detected

Third-Party Lab Integrity You Can Trust

Testing is conducted by Twin Arbor Analytical — a U.S.-based, ISO/IEC 17025-accredited laboratory.
This means:

  • Every batch is independently verified
  • Testing meets globally recognized scientific standards
  • Full ingredient traceability is maintained from raw material to finished capsule

Beware of Low-Grade Resveratrol: Choose Clinical-Grade Purity

Not all resveratrol is equal. Some products use diluted or low-potency extracts that lack consistent purity or efficacy. At HealthspanX, Ultra Pure Resveratrol™ is third-party tested to ensure it meets the same purity standards used in clinical research. When your health is on the line, only the highest quality will do.

Purity: Over 101% Ultra Pure Resveratrol

Tested using UPLC-DAD and verified by Twin Arbor Analytical — an ISO/IEC 17025-accredited lab. Every batch exceeds USP standards for identity, potency, and safety.

Dose: 1000mg Resveratrol Per Daily Serving

Each daily serving (2 capsules) delivers 1000mg of trans-resveratrol — aligned with doses used in clinical trials on metabolic, cognitive, and cardiovascular health.

Capsules Per Pack: 62 Pharmaceutical-Grade Capsules

One full month of high-potency resveratrol. Clean, easy-to-swallow capsules made with zero fillers or artificial additives.

Safety Tested: USA Lab-Tested for Heavy Metals & Microbes

Each batch is screened for arsenic, cadmium, lead, and mercury — with no detectable levels. Also tested for yeast, mold, E. coli, Salmonella, and Staphylococcus under USP protocols. All results fall well below global safety thresholds.

Vegan & Clean Formula

Made without dairy, soy, gluten, eggs, solvents, or synthetic additives. 100% vegan-friendly — designed for daily use in sensitive individuals.

Certifications: ISO 9001, HACCP, Kosher, and Halal Certified

Manufactured under strict international standards. Every capsule reflects our commitment to purity, safety, and universal accessibility.

3rd-Party Verified

Independently tested for purity, potency, and identity — with full COA (Certificate of Analysis) available for every batch.

Eco-Packaged: Sustainable Sachets, Not Plastic Bottles

We use recyclable, low-impact sachets instead of bulky plastic bottles — reducing waste and minimizing our environmental footprint without compromising product integrity. Better for the planet, safer for you.

What Is Resveratrol and How Does It Work?

Resveratrol is a polyphenol naturally found in red grapes, berries, and Japanese Knotweed. It supports healthy aging by activating SIRT1 and AMPK pathways, boosting mitochondrial function, reducing inflammation, and enhancing antioxidant defenses — all essential for long-term cellular resilience.

How Should I Take Ultra Pure Resveratrol™?

Take 2 capsules (500mg each) once daily, preferably in the morning with your first meal or any food containing healthy fats (like avocado or nuts). Fat improves resveratrol’s absorption, which helps your body get the most from every dose.

What Is the Right Dosage for Me?

Most human clinical studies use between 500mg and 1000mg daily, with good results seen in cardiovascular, metabolic, and cognitive outcomes. Ultra Pure Resveratrol™ provides 1000mg per day — aligned with top-tier clinical research.

When Will I Notice Results?

Many users report improved clarity, energy, or mood within the first 2–4 weeks. Deeper benefits like cardiovascular support, improved glucose regulation, and cellular resilience generally build over 8 to 12 weeks of consistent daily use.

Is Ultra Pure Resveratrol™ Safe to Take with Other Supplements or Medications?

Trans-resveratrol is generally considered safe and well-tolerated in healthy adults, but it can interact with certain medications. Studies show that resveratrol may:

  • Enhance the effects of blood thinners like warfarin, increasing the risk of bleeding. 
  • Influence drug metabolism by interacting with liver enzymes (e.g., cytochrome P450), potentially affecting the bioavailability of medications like itraconazole or hormonal treatments. 
  • Interfere with other antioxidants or herbal supplements, such as Ginkgo biloba or high-dose omega-3s. 

Because of these possible interactions, it’s important to consult your healthcare provider before taking resveratrol if you’re on prescription medications or complex supplement regimens. (Tellone et al., 2019; García et al., 2024; Chiba et al., 2016; Guthrie et al., 2017)

Is Ultra Pure Resveratrol™ Safe During Pregnancy or Breastfeeding?

Resveratrol has shown potential benefits in pregnancy-related animal studies, such as reducing oxidative stress and improving cardio-metabolic outcomes. However, due to its estrogen-like activity and the lack of robust human safety data, Ultra Pure Resveratrol™ is not currently recommended during pregnancy or breastfeeding unless advised by your healthcare provider. Always consult your physician before using any supplement while pregnant or nursing.

Can Children Take Resveratrol?

Ultra Pure Resveratrol™ is formulated for adult use. If considering it for children, consult a qualified healthcare professional.

Is Ultra Pure Resveratrol™ Vegan and Allergen-Free?

Yes. Our formula is 100% vegan and contains no dairy, soy, gluten, eggs, or artificial additives. It is non-GMO and formulated for purity and simplicity.

How Is the Purity of Ultra Pure Resveratrol™ Verified?

Every batch is tested using UPLC-DAD by Twin Arbor Analytical, an ISO/IEC 17025-accredited U.S. lab. Our current batch exceeds 101% purity and meets all USP standards for identity, safety, and performance.

Does Ultra Pure Resveratrol™ Contain Fillers or Additives?

No. Our capsules contain only pharmaceutical-grade resveratrol and a plant-based cellulose capsule. No fillers, binders, preservatives, or synthetics — just pure active ingredient.

Do You Offer a Subscription Option?

Yes. You can subscribe and save 15% with our flexible bimonthly subscription. You’ll get automatic delivery, priority stock access, and the ability to skip or cancel anytime — so you never run out.

Science

The Science of Healthy Aging Begins with Resveratrol

Resveratrol, a naturally occurring polyphenol (a plant compound with powerful health effects) found in grapes, berries, and red wine, supports healthy aging by acting on multiple cellular pathways. It activates longevity genes (genes that help cells live longer and stay healthier), improves mitochondrial performance (how well your cells make energy), reduces inflammation, and boosts antioxidant defenses (your body’s ability to fight off harmful molecules that damage cells). These interconnected effects make resveratrol a cornerstone of cellular health and a powerful tool in the fight against age-related decline. In simple terms, resveratrol helps your cells stay young, strong, and full of energy (Ungurianu et al., 2023; Kim et al., 2018).

SIRT1 Activation: Turning On Your Longevity Genes

Resveratrol directly activates SIRT1, a critical protein in the sirtuin family (proteins that help your cells age more slowly) that regulates metabolism, DNA repair, and cellular stress response. SIRT1 is an NAD+-dependent enzyme (it needs NAD+, a natural molecule in your body, to work properly). Resveratrol increases NAD+ availability indirectly by activating AMPK (a master switch that helps your cells make and use energy) and upregulating NAMPT, the rate-limiting enzyme (the slowest step in NAD+ recycling) in the NAD+ salvage pathway (your body’s system for reusing NAD+). This enhances SIRT1’s deacetylase activity (its ability to control which genes turn on and off) and amplifies its longevity-promoting effects. Together, this helps your body stay energized, youthful, and better able to repair itself (Grant, 2010; Lan et al., 2017; Peng et al., 2024; Chen et al., 2020).

Powering Up the Mitochondria

Aging is strongly linked to declining mitochondrial efficiency (your cells’ ability to make energy). Resveratrol boosts mitochondrial biogenesis (the creation of new energy-making structures in your cells) through SIRT1’s activation of PGC-1α, a master regulator of mitochondrial growth and function (a protein that tells your cells to make more and better mitochondria). This leads to increased ATP (the main energy unit in your body) and a decrease in damaging reactive oxygen species (ROS) (harmful molecules that can hurt cells), improving overall metabolic function and endurance. That means your body can produce more energy and feel less tired. (Price et al., 2012; Zhang et al., 2024).

Stronger Antioxidant Defenses with NRF2

Resveratrol enhances the body’s antioxidant capacity (its ability to protect against cell damage) by activating NRF2, a transcription factor (a protein that tells your genes what to do) that regulates antioxidant enzymes like SOD, catalase, and glutathione peroxidase (natural chemicals that defend your cells). These enzymes neutralize free radicals (unstable molecules that cause aging and damage), reducing oxidative stress, a major driver of cellular aging. In simple words, this helps your body clean up harmful stuff before it causes damage (Tufekci et al., 2021; Zhang et al., 2024). 

Fighting Inflammaging with NF-κB Modulation

Chronic inflammation, or "inflammaging" (slow, silent swelling inside the body as you age), is a hallmark of aging and age-related disease. Resveratrol helps suppress NF-κB, a pro-inflammatory signaling pathway (a chain reaction in the body that causes inflammation) that triggers cytokines like TNF-α and IL-6 (chemicals that increase swelling and pain). By calming this inflammatory storm, resveratrol helps protect tissues from long-term damage and contributes to heart, brain, and immune health. That means it helps cool down inflammation that could otherwise wear your body out faster (Csiszar, 2011; Iweala et al., 2024).

AMPK: The Master Metabolic Switch

Resveratrol also activates AMPK, the energy sensor of the cell (a protein that monitors your energy levels), which helps regulate metabolism, promote autophagy (a natural way your body cleans up old and damaged parts of cells), and increase mitochondrial health. AMPK and SIRT1 work together to boost cellular resilience (your body’s ability to bounce back from stress) and longevity. Together, they help your body run better, clean itself up, and stay younger longer (Salminen & Kaarniranta, 2012; Ido et al., 2015).

NAD+ Support: Fueling the Engine of Cellular Health

NAD+ (short for Nicotinamide Adenine Dinucleotide) is an essential molecule your cells use for energy production, DNA repair, and activating longevity-related proteins like SIRT1. Resveratrol indirectly boosts NAD+ levels by activating AMPK and increasing the expression of NAMPT (a key enzyme that helps rebuild NAD+), part of the NAD+ salvage pathway (your body’s NAD+ recycling system). Higher NAD+ levels enhance mitochondrial function, reduce oxidative damage, and improve overall metabolic resilience—benefits closely tied to resveratrol’s anti-aging effects. Think of NAD+ like fuel for your body’s repair and energy systems—and resveratrol helps you make more of it.

Real Health Benefits, Backed by Research

Cardiovascular Health

Resveratrol lowers blood pressure, improves cholesterol balance, and protects arteries from oxidative damage and plaque buildup (the sticky stuff that clogs arteries) (Das & Das, 2010; Carrizzo et al., 2013).

Metabolic Regulation

It improves insulin sensitivity (how well your body responds to insulin) and glucose metabolism, mimicking the effects of calorie restriction (eating less to stay healthy and live longer) to support healthy weight and blood sugar control (Pollack et al., 2013).

Brain Health

Resveratrol crosses the blood-brain barrier (it can enter the brain and work there) and protects neurons (brain cells) by reducing inflammation and oxidative damage. Studies show enhanced memory, mood, and cognitive resilience in aging brains (Quincozes‐Santos et al., 2011; Cao et al., 2018).

Immune Modulation

It enhances both innate and adaptive immunity (your fast and slow immune responses) while reducing chronic inflammation, helping the body respond better to infections and slow immune aging (Alesci et al., 2022).

Skin & Hormonal Support

Its antioxidant effects may benefit skin tone and texture, while its ability to interact with estrogen receptors (parts of the body that respond to the female hormone estrogen) shows promise in improving hormonal balance in postmenopausal women (Shin et al., 2015).

Human-Proven Safety with Ultra Pure Resveratrol™

Resveratrol is generally safe and well-tolerated, with over 240 clinical trials studying its impact. Our Resveratrol is ultra-pure, third-party tested, and formulated for maximum safety and performance, delivering exactly what your cells need without unnecessary fillers or contaminants.

Formula

Why Purity Matters in the Formula

The clinical benefits of resveratrol — from cardiovascular support to cellular longevity — have only been shown using pure trans-resveratrol, not proprietary blends or diluted extracts. That’s why Ultra Pure Resveratrol™ delivers over 101% tested purity of pharmaceutical-grade trans-resveratrol, with nothing else added.

Many brands cut costs by using low-purity powders or combining resveratrol with unrelated ingredients in a proprietary formula. But there’s no clinical evidence behind those shortcuts. We use only what’s proven — the exact form and purity trusted in human research — so you get results that are real, measurable, and aligned with science.

Why Capsules Still Lead the Way in Resveratrol Delivery

With powders, liquids, lozenges, and even sprays on the market, why do we still choose Ultra Pure Resveratrol™ in capsule form?
Because the science shows it’s the most protective, practical, and clinically relevant method for delivering resveratrol where it matters most—your bloodstream.

Protection from Breakdown in the Stomach

Trans-resveratrol, the active form, is sensitive to stomach acid and prone to degradation before it gets absorbed. Unprotected, it can isomerize or break down into less effective compounds (Koga et al., 2015; Tian & Liu, 2019). Capsules help shield resveratrol from this harsh environment, preserving its potency until it reaches the small intestine—where nutrient absorption actually happens (Walle, 2011; Friend, 2004).

Designed for Absorption Where It Works

The small intestine is the primary site where resveratrol is absorbed via passive diffusion (Walle, 2011). Our encapsulated formula helps ensure that more of the active compound survives digestion and reaches this absorption site, enhancing your chances of getting measurable benefits.

Low Bioavailability, Smart Delivery

Even though about 75% of resveratrol may be absorbed, less than 1% reaches the bloodstream due to rapid breakdown in the liver and gut (Walle, 2011). That’s why delivery matters. Capsule-based strategies—especially when using stable forms like trans-resveratrol—can improve systemic absorption without relying on experimental delivery systems (Briskey & Rao, 2020; Augustin et al., 2013).

Precise Dosing, Every Time

Each Ultra Pure Resveratrol™ capsule contains a consistent 500mg dose—the same purity and precision used in human clinical studies (Sokurenko et al., 2019; Smoliga & Blanchard, 2014). Powders and liquids may vary from dose to dose, but capsules offer predictability—critical for replicating clinical outcomes.

Easy, Portable, and Protected

Capsules are convenient, mess-free, and protect resveratrol from light, air, and moisture—three environmental factors that can degrade potency fast (Pezet et al., 1994; Juškaitė et al., 2017). This protection extends shelf life and helps preserve bioactivity from manufacture to the moment you take it.

Proven in Human Clinical Studies

Resveratrol capsules have been used in numerous human trials studying cardiovascular, anti-aging, and metabolic benefits. Although resveratrol’s bioavailability is naturally low, trials using oral capsules still show promising outcomes—especially when supported by smart formulation and consistent intake (Mohammadi-Sartang et al., 2017; Reis et al., 2024; Smoliga et al., 2011).

No Gimmicks—Just Science

While some companies chase trendy delivery systems like sprays or nano-mist formulations, Ultra Pure Resveratrol™ sticks to what works: a high-purity, properly dosed capsule backed by research. It’s a science-first approach that respects your body—and your wallet.

Usage

Recommended Daily Dosage

Take 2 capsules (500mg total) once daily with or without food.
This dosage reflects amounts used in human clinical trials and is consistent with studies showing benefits for cardiovascular, metabolic, and cognitive health.

When to Take It

Take Ultra Pure Resveratrol™ in the morning or with your first meal of the day.
Morning intake aligns with resveratrol’s impact on cellular energy, antioxidant defense, and inflammatory signaling, which follow a circadian rhythm.

How Long to Take It

Take Ultra Pure Resveratrol™ daily and consistently. Most users begin to feel improvements in energy, clarity, or well-being within 2–4 weeks. Clinical studies show more profound effects—including cardiovascular and cognitive benefits—emerge after 8 to 12 weeks of consistent use.

Scientifically Aligned

This protocol is informed by peer-reviewed research showing that daily resveratrol supplementation can:

  • Activate SIRT1 and AMPK pathways involved in longevity and metabolism
  • Improve vascular health, cholesterol profiles, and glucose regulation
  • Cross the blood-brain barrier to support cognitive resilience and reduce neuroinflammation

These benefits are supported by published studies in both clinical and preclinical settings (Cao et al., 2018; Pollack et al., 2013; Das & Das, 2010; Quincozes-Santos et al., 2011).

Lab Testing & Integrity

Lab Verified. Clinically Trusted. 100% Transparent.

At HealthspanX, we don’t just claim purity — we prove it. Every batch of Ultra Pure Resveratrol™ undergoes rigorous third-party testing in a certified U.S. laboratory to verify identity, potency, and safety — with results you can trust.

Identity & Potency Confirmed by UPLC-DAD

Each capsule contains Trans-Resveratrol (500mg), verified using Ultra Performance Liquid Chromatography with Diode Array Detection (UPLC-DAD) — a gold-standard method for confirming ingredient identity and purity.

  • Tested Purity: 101.1% — comfortably within USP specification (99–102%)
  • Batch ID: Res231003

Heavy Metal Testing (USP 233 Protocol)

We screen for heavy metals using validated methodologies to ensure your safety.
Our latest batch results were well below global safety thresholds:

  • Arsenic (As): ND (<2 ppm limit)
  • Cadmium (Cd): ND (<1 ppm limit)
  • Lead (Pb): ND (<2 ppm limit)
  • Mercury (Hg): ND (<0.1 ppm limit)

(ND = Not Detected above reporting threshold)

Microbial Screening (USP Standards)

Each batch is tested for microbial contamination in accordance with USP 2021 and USP 2022 standards to ensure it is safe and clean:

  • Total Yeast & Mold: <100 CFU/g
  • Total Aerobic Plate Count: <100 CFU/g
  • E. coli, Salmonella, Staphylococcus aureus: Not Detected

Third-Party Lab Integrity You Can Trust

Testing is conducted by Twin Arbor Analytical — a U.S.-based, ISO/IEC 17025-accredited laboratory.
This means:

  • Every batch is independently verified
  • Testing meets globally recognized scientific standards
  • Full ingredient traceability is maintained from raw material to finished capsule

Beware of Low-Grade Resveratrol: Choose Clinical-Grade Purity

Not all resveratrol is equal. Some products use diluted or low-potency extracts that lack consistent purity or efficacy. At HealthspanX, Ultra Pure Resveratrol™ is third-party tested to ensure it meets the same purity standards used in clinical research. When your health is on the line, only the highest quality will do.

Features

Purity: Over 101% Ultra Pure Resveratrol

Tested using UPLC-DAD and verified by Twin Arbor Analytical — an ISO/IEC 17025-accredited lab. Every batch exceeds USP standards for identity, potency, and safety.

Dose: 1000mg Resveratrol Per Daily Serving

Each daily serving (2 capsules) delivers 1000mg of trans-resveratrol — aligned with doses used in clinical trials on metabolic, cognitive, and cardiovascular health.

Capsules Per Pack: 62 Pharmaceutical-Grade Capsules

One full month of high-potency resveratrol. Clean, easy-to-swallow capsules made with zero fillers or artificial additives.

Safety Tested: USA Lab-Tested for Heavy Metals & Microbes

Each batch is screened for arsenic, cadmium, lead, and mercury — with no detectable levels. Also tested for yeast, mold, E. coli, Salmonella, and Staphylococcus under USP protocols. All results fall well below global safety thresholds.

Vegan & Clean Formula

Made without dairy, soy, gluten, eggs, solvents, or synthetic additives. 100% vegan-friendly — designed for daily use in sensitive individuals.

Certifications: ISO 9001, HACCP, Kosher, and Halal Certified

Manufactured under strict international standards. Every capsule reflects our commitment to purity, safety, and universal accessibility.

3rd-Party Verified

Independently tested for purity, potency, and identity — with full COA (Certificate of Analysis) available for every batch.

Eco-Packaged: Sustainable Sachets, Not Plastic Bottles

We use recyclable, low-impact sachets instead of bulky plastic bottles — reducing waste and minimizing our environmental footprint without compromising product integrity. Better for the planet, safer for you.

FAQ

What Is Resveratrol and How Does It Work?

Resveratrol is a polyphenol naturally found in red grapes, berries, and Japanese Knotweed. It supports healthy aging by activating SIRT1 and AMPK pathways, boosting mitochondrial function, reducing inflammation, and enhancing antioxidant defenses — all essential for long-term cellular resilience.

How Should I Take Ultra Pure Resveratrol™?

Take 2 capsules (500mg each) once daily, preferably in the morning with your first meal or any food containing healthy fats (like avocado or nuts). Fat improves resveratrol’s absorption, which helps your body get the most from every dose.

What Is the Right Dosage for Me?

Most human clinical studies use between 500mg and 1000mg daily, with good results seen in cardiovascular, metabolic, and cognitive outcomes. Ultra Pure Resveratrol™ provides 1000mg per day — aligned with top-tier clinical research.

When Will I Notice Results?

Many users report improved clarity, energy, or mood within the first 2–4 weeks. Deeper benefits like cardiovascular support, improved glucose regulation, and cellular resilience generally build over 8 to 12 weeks of consistent daily use.

Is Ultra Pure Resveratrol™ Safe to Take with Other Supplements or Medications?

Trans-resveratrol is generally considered safe and well-tolerated in healthy adults, but it can interact with certain medications. Studies show that resveratrol may:

  • Enhance the effects of blood thinners like warfarin, increasing the risk of bleeding. 
  • Influence drug metabolism by interacting with liver enzymes (e.g., cytochrome P450), potentially affecting the bioavailability of medications like itraconazole or hormonal treatments. 
  • Interfere with other antioxidants or herbal supplements, such as Ginkgo biloba or high-dose omega-3s. 

Because of these possible interactions, it’s important to consult your healthcare provider before taking resveratrol if you’re on prescription medications or complex supplement regimens. (Tellone et al., 2019; García et al., 2024; Chiba et al., 2016; Guthrie et al., 2017)

Is Ultra Pure Resveratrol™ Safe During Pregnancy or Breastfeeding?

Resveratrol has shown potential benefits in pregnancy-related animal studies, such as reducing oxidative stress and improving cardio-metabolic outcomes. However, due to its estrogen-like activity and the lack of robust human safety data, Ultra Pure Resveratrol™ is not currently recommended during pregnancy or breastfeeding unless advised by your healthcare provider. Always consult your physician before using any supplement while pregnant or nursing.

Can Children Take Resveratrol?

Ultra Pure Resveratrol™ is formulated for adult use. If considering it for children, consult a qualified healthcare professional.

Is Ultra Pure Resveratrol™ Vegan and Allergen-Free?

Yes. Our formula is 100% vegan and contains no dairy, soy, gluten, eggs, or artificial additives. It is non-GMO and formulated for purity and simplicity.

How Is the Purity of Ultra Pure Resveratrol™ Verified?

Every batch is tested using UPLC-DAD by Twin Arbor Analytical, an ISO/IEC 17025-accredited U.S. lab. Our current batch exceeds 101% purity and meets all USP standards for identity, safety, and performance.

Does Ultra Pure Resveratrol™ Contain Fillers or Additives?

No. Our capsules contain only pharmaceutical-grade resveratrol and a plant-based cellulose capsule. No fillers, binders, preservatives, or synthetics — just pure active ingredient.

Do You Offer a Subscription Option?

Yes. You can subscribe and save 15% with our flexible bimonthly subscription. You’ll get automatic delivery, priority stock access, and the ability to skip or cancel anytime — so you never run out.

Feel the Difference in Just Weeks — Support Heart, Brain, and Cellular Health

Ultra Pure Resveratrol™ supports healthy aging at the cellular level — helping defend your cells from oxidative stress, improve circulation, and activate key longevity pathways. Within weeks, users often report noticeable benefits in heart health, mental clarity, energy, and overall vitality.

Cardiovascular Health

Promote healthy blood pressure, endothelial function, and vascular elasticity. Resveratrol helps support circulation and reduce oxidative stress in arterial walls.

Cognitive Support

Resveratrol crosses the blood-brain barrier to protect neurons from inflammation and oxidative damage. Clinical research shows improvements in memory, focus, and cognitive resilience over time.

Enhanced Energy

Support mitochondrial performance and cellular energy output by activating SIRT1 and AMPK — key regulators of metabolic health and fatigue resistance.

Skin Health

Combat oxidative skin damage and support collagen maintenance from the inside out. Resveratrol helps defend skin cells from environmental stress and promotes a more radiant, youthful appearance.

Longevity Support 

Activate SIRT1 — your body’s longevity enzyme — while supporting DNA repair and NAD+ metabolism. Resveratrol helps your cells stay stronger, longer.

 

These are just a few of the powerful effects. In our Resveratrol science section, you’ll discover even more clinically studied benefits — including improved metabolic regulation, immune balance, gut health, and antioxidant defense. See how Resveratrol supports your body from the inside out.

99% Customers Are Satisfied

What Verified Customers Are Saying About Ultra Pure Resveratrol™

More Focus, Less Brain Fog — I Feel Sharper Than I Have in Years

I started taking Ultra Pure Resveratrol™ to support my brain health, and within a few weeks, the difference was noticeable. My focus is clearer and I’m remembering names more easily. 

David M.

  • Verified Buyer

My Blood Pressure’s Down — And I’ve Got My Energy Back

I’ve struggled with borderline high blood pressure for years. After taking resveratrol daily for two months, my numbers are finally trending down — and I’ve got more energy for my morning walks.

Susan R.

  • Verified Buyer

Less Inflammation, Better Sleep, and Real Results

I originally tried resveratrol for joint pain, but I was surprised at how much better I felt overall. I sleep deeper, my knees aren’t as stiff, and my skin even looks healthier. Highly recommended.

Greg T.

  • Verified Buyer

Complete Your NAD+ Support Regimen

Pair Ultra Pure Resveratrol™ With Ultra Pure NMN™ & Ultra Pure Quercetin™

Ultra Pure Resveratrol™ activates sirtuin genes to enhance Ultra Pure NMN™ efficacy and optimize NAD+ production for longevity. 

Ultra Pure Quercetin™ acts as a potent senolytic, clearing aging cells and boosting NAD+ benefits while supporting immune health. 

Together, they amplify NMN's impact on cellular vitality and healthy aging.

HealthspanX 60-Day Confidence Guarantee

We stand behind Ultra Pure Resveratrol™ with a no-hassle 60-day money-back guarantee. If you're not satisfied for any reason, we’ll make it right—quickly and easily through our Return Portal.

Why so confident? Because our Resveratrol is the same pharmaceutical-grade compound used in human clinical trials—tested, verified, and trusted. For more information, please check our Return and Refund Policy.

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Why Choose HealthspanX?

Where Clinical-Grade Purity Meets Purpose

HealthspanX was founded by a visionary whose life was transformed by the science of NAD+ restoration. What began as a personal breakthrough became a mission to bring clarity, credibility, and clinical-grade solutions to those serious about aging well.

 

We don’t chase trends—we deliver evidence. Our Ultra Pure Resveratrol™ is the same pharmaceutical-grade ingredient used in human clinical trials, verified for 101%+ purity and tested by third-party U.S. labs. Every formula is backed by research, not marketing.

 

At HealthspanX, we translate complex longevity science into real-world results—without the hype, the guesswork, or the waste. Because longevity isn’t a trend. It’s your future, and we’re here to help you protect it.

Have a Question or Need Support? 

The HealthspanX team is ready to help with fast, personalized assistance.
📩 Email us anytime at support@healthspanx.org — we typically respond within 24 hours.